How to treat Covid-19

The indications which are presented below are the guidelines which physicians working at IppocrateOrg Call Centre are currently referring to when treating Covid-19 patients.

We want to emphasise that drugs and supplements and their dosage are to be considered as a mere indication. The treating physician must determine and prescribe the appropriate therapy for each patient.

So NEVER without a doctor!

IMPORTANT NOTICE

Covid-19 is a complex syndrome for which a specific treatment has not been identified yet.

Our therapeutical approach is a personalised treatment, based on the available scientific evidence, on the biological plausibility and on each patient situation. The only purpose of this publication is not to give guidelines or therapeutical indications, but to open a dialogue between physicians to get a better treatment of the patients involved in this current pandemic.

All the published indications are for practitioners only.

In order to get the best ‘at home therapy’ for outpatients, basic guidelines proposed (updated to 27th March 2021) by IppocrateOrg, consider the progression of the disease in 3 stages, as they are well known from the majority of clinicians:

STAGE PATHOPHYSIOLOGY CLINIC
STAGE 1
(Early Infection)
Virus replication Flu-like symptoms (fever, joint and muscle pain, headache, weakness..)
STAGE 2
(Pulmonary Phase)
Lung complication Cough, dyspnoea, polypnoea
STAGE 2A
W/out hypoxia
STAGE 2B
With hypoxia
STAGE 3
(Hyperinflammation Phase)
Cytokine storm or hypercytokinemia SARS, vasculitis, microembolism, microthrombosis, multi-organ failure

We define STAGE ZERO as a test-positive patient without symptoms.
We suggest application of STAGE ZERO therapy to all close contacts.

The recovery from Covid is often very long. We propose the following treatments to shorten it.

Early treatment is the winning strategy

STAGE Zero
(Asymptomatic and test-positive patient)

DRUG DOSAGE CONTRAINDICATIONS
Vitamin D3 50.000 IU/day for 6 days (if not in prophylaxis)
10.000 IU./day for 6 days (if in prophylaxis)
And then 4.000 IU/day
While eating a greasy meal (for example at lunch
Children: 200 IU/Kg/day (until negative test)

Severe Chronic Kidney Insufficiency (CKD)
Hypercalcemia

Vitamin C From 1 g/day, in consideration of formulation Severe CKD, deficit G6PD
Zinc picolinate 30-50 mg/day  
Esperidine 100 mg/day  
Quercetin Up to 250 mg x 2/day  
Lactoferrin Up to 200 mg x 2/day  
Bromexine 8 mg x 3/day  
Pelargonium S. > 12 y-o: 20 mg x 3/day for 7 days
6-12 y-o: 13 mg x 3/day for 7 days
Hemorrhagic diathesis
F.E in patient in treatment with blood thinners
Suffumigation 3 times/day  
Hydrossitirosol and α-cyclodestrine 2-3 puffs x 3-4/day in the throat  

Other active ingredients known for their antiviral action

Vitamin A Up to 30.000 IU/day Pregnancy
Resveratrol Up to 1000 mg/day  

The proper combination of medications from the list will be prescribed by the physician, according to the patient’s needs and characteristics.

Our indication – in any case – is to prescribe:
  ✔ Vitamin D
  ✔ Zinc
  ✔ Vitamin C

which we recommend to be prescribed even in severe stages of the disease.

Hence if the patient is treated in stage 1 or 2, do not forget about prescribing these supplements in conjunction with the other drugs.

⬇️

STAGE 1
(flu-like symptoms)

DRUG DOSAGE CONTRAINDICATIONS
ASA Up to 100 mg/day till asymptomatic  
Ivermectine

0,2 mg/kg
(12 mg to 20/ daily)
for 5 days

In the setting of poor clinical response , advanced disease , or obesity , higher doses should be used (target o,4-0,6 mg/kg)

 
Hydroxychloroquine (HCQ) 200 mg x 2/day for 7 days Arrhythmias,
Retinopathy
Def. G6PDH
Azithromycin
or
Doxycycline
500 mg/day for 3 days, stop 2 days, then repeat LQTS
100 mg x 2/day for 7 days  
Colchicine 0.5 mg x 2/day for 14 days Cardiac Insuff., CKD
do not use with Clarithromicin

⬇️

STAGE 2A
(lung complication without hypoxia)

DRUG DOSAGE CONTRAINDICATIONS
Montelukast 10 mg 2 hours after dinner for 14 days  
Amoxi/Clavulanic acid
or
Other antibiotics
875 mg+125 mg x 3/day for 8-10 days  
In association with Azithromycin in case of superinfection  
Acetylcysteine 600 mg up to x 3/day fro 7 days  
Levodropropizine 60 mg as needed, up to x 3/day  
Enoxaparin 4.000 IU x 1-2/day for 10 days if weight < 70 Kg
6.000 IU x 1-2/day for 10 days if weight 70-100 Kg
Hemorrhagic diathesis
Thrombocytopenia

N.B.: Practitioner will evaluate if patient will need corticosteroid on therapy as in stage 2B.

It is advisable to do thoracic ecography and/or ct scan

⬇️

STAGE 2B
(lung complication with hypoxia)

DRUG DOSAGE CONTRAINDICATIONS
O2-therapy 1-6 L/min if SpO2 < 92% in AA  
Enoxaparin 100 IU/Kg/12 hours  
Dexamethasone ⚠️ 6 mg/morning OR 3 mg x 2/day do not associate but use alternatively
associate gastroprot.
Betamethasone ⚠️ 8 mg/morning OR 4 mg x 2/day
Methylprednisolone ⚠️ 32 mg/morning OR 16 mg x 2/day
Prednisone ⚠️ 40 mg/morning OR 20 mg x 2/day
Deflazacort ⚠️ 30 mg x 2/day
Antibiotics According to practitioner’s judgment  

⚠️ Corticosteroids: NEVER AT THE BEGINNING, but only at the end of the viral stage!!
for 6-7 days then diminish
better one morning dose
2 doses if patient is suffering (always Deflazacort, for its fast action)
Contraindications: Hypertension
, Hyperglycaemia, …

In case Oxygen > 6 L/min

or

SpO2 persistently < 92%

⬇️

HOSPITALISATION IS MANDATORY

Download PDF